The San Francisco 49ers’ injury woes continue. In their game against the Tampa Bay Buccaneers, another superstar, Fred Warner, was seriously injured.

The San Francisco 49ers have been plagued by injuries this season.

This injury woes worsened in the game against the Tampa Bay Buccaneers.

28-year-old linebacker Fred Warner suffered a serious ankle injury. The defensive star had to be taken off the field in a cart.

After the game, 49ers coach Kyle Shanahan gave an injury update and confirmed the worst fears: Warner will miss the rest of the season!

His injury is a dislocated and broken ankle, which will require surgery.

Devastating: The full play on which Fred Warner injured his knee/leg. This looks terrible….

Warner was carted off with an aircast on his leg.

Pray for him pic.twitter.com/PW2KY9RiWy

— Dov Kleiman (@NFL_DovKleiman) October 12, 2025

Warner is not the only prominent player to be sidelined for San Francisco this season. With Brock Purdy, George Kittle, Brandon Aiyuk, Ricky Pearsall, and Nick Bosa, numerous 49ers stars have already been injured this year.

Warner was drafted in the third round in 2018 and has been a key defensive player for his team ever since. He is considered the leader of the defense, known for his many tackles, interceptions, and sacks, and has been named All-Pro several times. He has reached the playoffs several times with the 49ers and played in the Super Bowl twice.